Article

Exploiting aberrant mRNA expression in autism for gene discovery and diagnosis

2015-10-19

Abstract excerpt

Autism spectrum disorder (ASD) is characterized by substantial phenotypic and genetic heterogeneity, which greatly complicates the identification of genetic factors that contribute to the disease. Study designs have mainly focused on group differences between cases and controls. The problem is that, by their nature, group difference-based methods (e.g., differential expression analysis) blur or collapse the hetero...

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Literature Corpus work: 65b07dd8-7b21-579f-9156-9a6ab479c253
DOI: 10.1101/029488

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