Influenza virus intracellular replication dynamics, release kinetics, and particle morphology during propagation in MDCK cells

Abstract excerpt

Influenza viruses are respiratory pathogens and can cause severe disease. The best protection against influenza is provided by annual vaccination. These vaccines are produced in embryonated chicken eggs or using continuous animal cell lines. The latter processes are more flexible and scalable to meet the growing global demand. However, virus production in cell cultures is more expensive. Hence, further research...

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