Article
PNPLA3 Expression Is Related to Liver Steatosis in Morbidly Obese Women with Non-Alcoholic Fatty Liver Disease.
International journal of molecular sciences - 27 Apr 2016
Aragonès Gemma, Auguet Teresa, Armengol Sandra, Berlanga Alba, Guiu-Jurado Esther, Aguilar Carmen, Martínez Salomé, Sabench Fátima, Porras José Antonio, Ruiz Maikel Daniel, Hernández Mercé, Sirvent Joan Josep, Del Castillo Daniel, Richart Cristóbal
Abstract excerpt
Recent reports suggest a role for the Patatin-like phospholipase domain-containing protein 3 (PNPLA3) in the pathology of non-alcoholic fatty liver disease (NAFLD). Lipid deposition in the liver seems to be a critical process in the pathogenesis of NAFLD. The aim of the present work was to evaluate the association between the liver PNPLA3 expression, key genes of lipid metabolism, and the presence of NAFLD in...
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