Article
Elevation of plasma-soluble HLA-G in childhood nephrotic syndrome is associated with IgE.
Annals of clinical biochemistry - 1 Jan 2017
Liu Yanqing, Lai Meimei, Lou Yunyan, Han Qiuyue, Yang Qing, Chen Minguang, Li Jingbo, Wang Huiyan, Yan Weihua, Zheng Xiaoqun
Abstract excerpt
Background Nephrotic syndrome is related to immune system dysfunction. Soluble human leukocyte antigen-G has been suggested to have an immunomodulatory role. Additionally, human leukocyte antigen-G expression may be influenced by the 14-base pair insertion/deletion polymorphism. However, this molecule has not been investigated in nephrotic syndrome. Methods Fifty-five children with nephrotic syndrome were...
Topics
- Adolescent
- Alleles
- Anti-Inflammatory Agents
- Biomarkers
- Case-Control Studies
- Child
- Child, Preschool
- Female
- Gene Expression
- Gene Frequency
- HLA-G Antigens
- Humans
- INDEL Mutation
- Immunity, Innate