Article
Non-classical monocytes predict progression of carotid artery bifurcation intima-media thickness in HIV-infected individuals on stable antiretroviral therapy.
HIV clinical trials - 1 May 2016
Chow Dominic C, Kagihara Jamie M, Zhang Guangxiang, Souza Scott A, Hodis Howard N, Li Yanjie, Mitchell Brooks I, Nakamoto Beau K, Kallianpur Kalpana J, Keating Sheila M, Norris Philip J, Kohorn Lindsay B, Ndhlovu Lishomwa C, Shikuma Cecilia M
Abstract excerpt
BACKGROUND: Inflammation may contribute to cardiovascular disease (CVD) among antiretrovirally suppressed HIV-infected individuals. We assessed relationships of monocyte, CD8 T-cell activation and plasma biomarkers to changes in carotid artery intima-media thickness (CIMT). METHODS: Longitudinal study of HIV-infected subjects ≥40 years and on stable antiretroviral therapy (ART) ≥3 months. Peripheral blood...
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