Article
Predictive effects of bilirubin on response of colorectal cancer to irinotecan-based chemotherapy.
World journal of gastroenterology - 28 Apr 2016
Yu Qian-Qian, Qiu Hong, Zhang Ming-Sheng, Hu Guang-Yuan, Liu Bo, Huang Liu, Liao Xin, Li Qian-Xia, Li Zhi-Huan, Yuan Xiang-Lin
Abstract excerpt
AIM: To examine the predictive effects of baseline serum bilirubin levels and UDP-glucuronosyltransferase (UGT) 1A1*28 polymorphism on response of colorectal cancer to irinotecan-based chemotherapy. METHODS: The present study was based on a prospective multicenter longitudinal trial of Chinese metastatic colorectal cancer (mCRC) patients treated with irinotecan-based chemotherapy (NCT01282658). Baseline serum...
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