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Article

Association between UGT1A1*28 polymorphisms and clinical outcomes of irinotecan-based chemotherapies in colorectal cancer: a meta-analysis in Caucasians.

PloS one - 1 Jan 2013

Liu Xiang, Cheng Dangxiao, Kuang Qin, Liu Geoffrey, Xu Wei

Abstract excerpt

BACKGROUND: Whether UGT1A1*28 genotype is associated with clinical outcomes of irinotecan (IRI)-based chemotherapy in Colorectal cancer (CRC) is an important gap in existing knowledge to inform clinical utility. Published data on the association between UGT1A1*28 gene polymorphisms and clinical outcomes of IRI-based chemotherapy in CRC were inconsistent. METHODOLOGY/PRINCIPAL FINDINGS: Literature retrieval,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23516488
DOI: 10.1371/journal.pone.0058489
PMCID: PMC3597733

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Association between UGT1A1*28 polymorphisms and clinical outcomes of irinotecan-based chemotherapies in colorectal cancer: a meta-analysis in Caucasians.PMID 23516488Read ↗

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Association of UGT1A1*28 polymorphisms with irinotecan-induced toxicities in colorectal cancer: a meta-analysis in Caucasians.Semantic proximity Read ↗

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