Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of Conformational Stability of Abnormal Prion Protein Aggregates across the Spectrum of Creutzfeldt-Jakob Disease Prions.

Journal of virology - 15 Jul 2016

Cescatti Maura, Saverioni Daniela, Capellari Sabina, Tagliavini Fabrizio, Kitamoto Tetsuyuki, Ironside James, Giese Armin, Parchi Piero

Abstract excerpt

UNLABELLED: The wide phenotypic variability of prion diseases is thought to depend on the interaction of a host genotype with prion strains that have self-perpetuating biological properties enciphered in distinct conformations of the misfolded prion protein PrP(Sc) This concept is largely based on indirect approaches studying the effect of proteases or denaturing agents on the physicochemical properties of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Creutzfeldt-Jakob Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Guanine

Share to Protein Conformation

Share to Protein Denaturation

Share to Protein Stability

Share to PrPSc Proteins

Share to Temperature

Source

Open in PubMed Open full text

Identifiers

PMID: 27122583
DOI: 10.1128/JVI.00144-16
PMCID: PMC4936149

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of Conformational Stability of Abnormal Prion Protein Aggregates across the Spectrum of Creutzfeldt-Jakob Disease Prions.PMID 27122583Read ↗

Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes.Semantic proximity Read ↗

Biochemical and strain properties of CJD prions: complexity versus simplicity.Semantic proximity Read ↗

Prion Strain Characterization of a Novel Subtype of Creutzfeldt-Jakob Disease.Semantic proximity Read ↗

A closer look at prion strains: characterization and important implications.Semantic proximity Read ↗

Molecular classification of sporadic Creutzfeldt-Jakob disease.Semantic proximity Read ↗

Review: Creutzfeldt-Jakob disease: prion protein type, disease phenotype and agent strain.Semantic proximity Read ↗

Analyses of protease resistance and aggregation state of abnormal prion protein across the spectrum of human prions.Semantic proximity Read ↗

Protease-sensitive conformers in broad spectrum of distinct PrPSc structures in sporadic Creutzfeldt-Jakob disease are indicator of progression rate.Semantic proximity Read ↗

Molecular pathogenesis of sporadic prion diseases in man.Semantic proximity Read ↗

Structural determinants of phenotypic diversity and replication rate of human prions.Semantic proximity Read ↗

Novel prion protein conformation and glycotype in Creutzfeldt-Jakob disease.Semantic proximity Read ↗

The prion diseases: Creutzfeldt-Jakob, Gerstmann-Sträussler-Scheinker, and related disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.