Article
PI3K as a Potential Therapeutic Target in Thymic Epithelial Tumors.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Aug 2016
Alberobello Anna Teresa, Wang Yisong, Beerkens Frans Joseph, Conforti Fabio, McCutcheon Justine N, Rao Guanhua, Raffeld Mark, Liu Jing, Rahhal Raneen, Zhang Yu-Wen, Giaccone Giuseppe
Abstract excerpt
INTRODUCTION: Thymic epithelial tumors (TETs) are rare tumors originating from the epithelium of the thymus with limited therapeutic options beyond surgery. The pathogenesis of TETs is poorly understood, and the scarcity of model systems for these rare tumors makes the study of their biology very challenging. METHODS: A new cell line (MP57) was established from a thymic carcinoma specimen and characterized using...
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