Article
Analysis of a Spontaneous Non-Motile and Avirulent Mutant Shows That FliM Is Required for Full Endoflagella Assembly in Leptospira interrogans.
PloS one - 1 Jan 2016
Fontana Célia, Lambert Ambroise, Benaroudj Nadia, Gasparini David, Gorgette Olivier, Cachet Nathalie, Bomchil Natalia, Picardeau Mathieu
Abstract excerpt
Pathogenic Leptospira strains are responsible for leptospirosis, a worldwide emerging zoonotic disease. These spirochetes are unique amongst bacteria because of their corkscrew-like cell morphology and their periplasmic flagella. Motility is reported as an important virulence determinant, probably favoring entry and dissemination of pathogenic Leptospira in the host. However, proteins constituting the periplasmic...
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