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Article

Methionine synthase 2756AA polymorphism is associated with the risk of cognitive impairment in patients with late-life depression.

Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists - 1 Mar 2017

Yang Ya-Hsu, Chiu Chih-Chiang, Teng Hao-Wei, Chu Chih-Pang, Chang Ching-Jui, Chiu Wei-Che, Chen Chin-Hsin, Lu Mong-Liang, Liu Shen-Ing, Huang Shih-Yi, Liu Hsing-Cheng, Sun I-Wen

Abstract excerpt

BACKGROUNDS: Apolipoprotein E epsilon-4 (APOE ε4) allele, methylenetetrahydrofolate reductase (MTHFR C677T), and methionine synthase (MTR A2756G) were tested their associations with cognitive impairment in people with late-life depression (LLD). METHODS: People with LLD were assessed by mini-mental state examination and were examined the distribution of APOE ε4 allele, MTHFR, and MTR polymorphisms. RESULTS: Odds...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27111719
DOI: 10.1111/appy.12242

Genes

MTR
APOE
MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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