Article
Serum Immunoglobulin G Levels to Porphyromonas gingivalis Peptidylarginine Deiminase Affect Clinical Response to Biological Disease-Modifying Antirheumatic Drug in Rheumatoid Arthritis.
PloS one - 1 Jan 2016
Kobayashi Tetsuo, Ito Satoshi, Kobayashi Daisuke, Shimada Atsushi, Narita Ichiei, Murasawa Akira, Nakazono Kiyoshi, Yoshie Hiromasa
Abstract excerpt
OBJECTIVES: To determine whether serum immunity to Porphyromonas gingivalis peptidylarginine deiminase (PPAD) affects the clinical response to biological disease-modifying antirheumatic drug (bDMARD) in patients with rheumatoid arthritis (RA). METHODS: In a retrospective study, rheumatologic and periodontal conditions of 60 patients with RA who had been treated with conventional synthetic DMARD were evaluated...
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