Article
Complex Chromosomal Rearrangements in B-Cell Lymphoma: Evidence of Chromoanagenesis? A Case Report.
Neoplasia (New York, N.Y.) - 1 Apr 2016
Ortega Veronica, Chaubey Alka, Mendiola Christina, Ehman William, Vadlamudi Kumari, Dupont Barbara, Velagaleti Gopalrao
Abstract excerpt
Genomic instability is a well-known hallmark of cancer. Recent genome sequencing studies have led to the identification of novel phenomena called chromothripsis and chromoanasynthesis in which complex genomic rearrangements are thought to be derived from a single catastrophic event rather than by several incremental steps. A new term chromoanagenesis or chromosomal rebirth was coined recently to group these two...
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