Article
The role of variations within microRNA in inflammatory bowel disease.
European journal of gastroenterology & hepatology - 1 Apr 2013
Papaconstantinou Ioannis, Stamatis Konstantinos, Tzathas Charalambos, Vassiliou Ioannis, Giokas Georgios, Gazouli Maria
Abstract excerpt
MicroRNAs (miRNAs) are small noncoding RNAs that are implicated in gene expression regulation at both a transcriptional and at a translational level. Single-nucleotide polymorphisms may occur in miRNA biogenesis pathway genes, primary miRNA, pre-miRNA, or a mature miRNA sequence. Such polymorphisms may be functional with respect to biogenesis and actions of mature miRNA. These single-nucleotide polymorphisms may...
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