Article
A Single-Nucleotide Polymorphism in 3'-Untranslated Region of Endothelin-1 Reduces Risk of Dementia After Ischemic Stroke.
Medical science monitor : international medical journal of experimental and clinical research - 23 Apr 2016
Ma Wanwan, Fu Qizhi, Zhang Yanpeng, Zhang Zhen
Abstract excerpt
BACKGROUND Ischemic stroke is widely recognized as a major health problem and social burden worldwide, and it usually leads to dementia. In this study, we aimed to better understand the pathogenesis in the development of dementia following ischemic stroke. MATERIAL AND METHODS We exploited miRNA database to search for the target for miR-125a and validated the found target using luciferase assay. Further, we...
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