Article
Significant Destructive Interaction of BDNF Val>Met Polymorphism with Stroke Severity and Family History of Dementia for Cognitive Impairments.
Acta neurologica Taiwanica - 30 Sept 2020
Rezaei Sajjad, Mobarake Karim Asgari, Saberi Alia, Keshavarz Parvaneh
Abstract excerpt
PURPOSE: The patients with more severe stroke, have more chance to develop higher levels of cognitive impairments; and family history of dementia as a genetic background, can give rise to an increased risk of the severity of cognitive deterioration. In this study, we sought to investigate whether the risk alleles of Val66Met of brain-derived neurotrophic factor (BDNF) polymorphism, has a destructive interaction...
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