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Article

Two variants on T2DM susceptible gene HHEX are associated with CRC risk in a Chinese population.

Oncotarget - 17 May 2016

Sun Rui, Liu Jian-Ping, Gao Chang, Xiong Ying-Ying, Li Min, Wang Ya-Ping, Su Yan-Wei, Lin Mei, Jiang An-Li, Xiong Ling-Fan, Xie Yan, Feng Jue-Ping

Abstract excerpt

Increasing amounts of evidence has demonstrated that T2DM (Type 2 Diabetes Mellitus) patients have increased susceptibility to CRC (colorectal cancer). As HHEX is a recognized susceptibility gene in T2DM, this work was focused on two SNPs in HHEX, rs1111875 and rs7923837, to study their association with CRC. T2DM patients without CRC (T2DM-only, n=300), T2DM with CRC (T2DM/CRC, n=135), cancer-free controls...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 27105501
DOI: 10.18632/oncotarget.8865
PMCID: PMC5045432

Genes

HHEX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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