Article
Genetic variation of ErbB4 confers risk of colorectal cancer in a Chinese Han population.
Cancer biomarkers : section A of Disease markers - 1 Jan 2014
Gao Xueren, Zhang Shulong, Zhu Zhansheng
Abstract excerpt
BACKGROUND: Colorectal cancer (CRC) is the most common cancer worldwide. Both genetic and environmental factors play an important role in pathogenesis of CRC, susceptibility may be modified by functional polymorphisms in receptor tyrosine kinase genes, such as ErbB4. We here evaluated whether a 12-bp insertion/deletion (indel) polymorphism (rs6147150) in the 3'UTR of ErbB4 could potentially affect the occurrence...
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