Article
Clinical, Pathological, and Molecular Features of Lung Adenocarcinomas with AXL Expression.
PloS one - 1 Jan 2016
Sato Katsuaki, Suda Kenichi, Shimizu Shigeki, Sakai Kazuko, Mizuuchi Hiroshi, Tomizawa Kenji, Takemoto Toshiki, Nishio Kazuto, Mitsudomi Tetsuya
Abstract excerpt
The receptor tyrosine kinase AXL is a member of the Tyro3-Axl-Mer receptor tyrosine kinase subfamily. AXL affects several cellular functions, including growth and migration. AXL aberration is reportedly a marker for poor prognosis and treatment resistance in various cancers. In this study, we analyzed clinical, pathological, and molecular features of AXL expression in lung adenocarcinomas (LADs). We examined 161...
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