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Article

Role of the Receptor Tyrosine Kinase Axl and its Targeting in Cancer Cells

6 Apr 2016

Abstract excerpt

Aberrant expression and activation of receptor tyrosine kinases (RTK) is a frequent feature of tumor cells that may underlie tumor aggressiveness. Among RTK, Axl, a member of the Tyro3-Axl-Mer family, represents a potential therapeutic target in different tumor types given its over-expression which leads to activation of oncogenic signaling promoting cell proliferation and survival, as well as migration and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 27048336
DOI: 10.2174/0929867323666160405112954

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