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Article

Preclinical and Clinical Research Models of Prostate Cancer: A Brief Overview

14 Oct 2022

Abstract excerpt

The incidence and mortality from prostate cancer (PCa) are on the rise which poses a major public health concern worldwide. In this narrative review, we have summarized the characteristics of major in vitro and in vivo PCa models including their utility in developing treatment strategies. Androgens, particularly, testosterone and dihydrotestosterone (DHT) activate the androgen receptor (AR) signaling pathway that...

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PMID: 36295041
DOI: 10.3390/life12101607

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