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Article

Methylenetetrahydrofolate reductase polymorphisms as risk factors for retinal venous occlusive disease: A literature review.

European journal of ophthalmology - 1 May 2021

Marques Manuel, Alves Francisco, Leitão Miguel, Rodrigues Catarina, Ferreira Joana Tavares

Abstract excerpt

The role of polymorphisms of methylenetetrahydrofolate reductase (MTHFR) gene in retinal vein occlusion (RVO) is a theme of discussion since the first reports of RVO in patients with MTHFR C677T mutation and without classic acquired risk factors for retinal vascular disease. The association between MTHFR polymorphisms and RVO has been studied over the last 20 years producing conflicting results. This review aims...

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PMID: 33715478
DOI: 10.1177/11206721211000647

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