Article
Plasma urotensin-2 level and Thr21Met but not Ser89Asn polymorphisms of the urotensin-2 gene are associated with migraines.
The journal of headache and pain - 1 Jan 2016
Geyik Sırma, Ergun Sercan, Kuzudişli Samiye, Şensoy Figen, Temiz Ebru, Altunışık Erman, Korkmaz Murat, Dağlı Hasan, Kul Seval, Akçalı Aylin, Neyal Ayşe Münife
Abstract excerpt
BACKGROUND: Urotensin-II (U-II) is a peptide recognized by its potent vasoconstrictor activity in many vascular events, however the role of urotensin-II in migraine has not been considered yet. The molecular mechanisms and genetics of migraine have not been fully clarified yet, but it is well-known that vascular changes considerably contribute in pathophysiology of migraine and also its complications. The aim of...
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