Article
Endothelial nitric oxide synthase (Glu298Asp) polymorphism is an independent risk factor for migraine with aura.
Headache - 1 Jan 2000
Borroni Barbara, Rao Renata, Liberini Paolo, Venturelli Elisabetta, Cossandi Michela, Archetti Silvana, Caimi Luigi, Padovani Alessandro
Abstract excerpt
OBJECTIVE: The aim of the present study was to evaluate whether the functional endothelial nitric oxide synthase (eNOS) Glu298Asp polymorphism, which has been demonstrated to decrease the endothelial NOS activity, might be a risk factor for migraine. BACKGROUND: It has widely demonstrated that nitric oxide (NO) is involved in migraine pathogenesis. Several genetic risk factors have been associated with migraine,...
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