Article
MicroRNA-155 Promotes the Directional Migration of Resident Smooth Muscle Progenitor Cells by Regulating Monocyte Chemoattractant Protein 1 in Transplant Arteriosclerosis.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2016
Sun Yuan, Wang Ke, Ye Ping, Wu Jie, Ren Lingyun, Zhang Anchen, Huang Xiaofan, Deng Peng, Wu Chuangyan, Yue Zhang, Chen Zhaolei, Ding Xiangchao, Chen Jiuling, Xia Jiahong
Abstract excerpt
OBJECTIVE: Smooth muscle-like cells are major cell components of transplant arteriosclerosis lesions. This study investigated the origin of the smooth muscle-like cells, the mechanisms responsible for their accumulation in the neointima, and the factors that drive these processes. APPROACH AND RESULTS: A murine aortic transplantation model was established by transplanting miR-155(-/-) bone marrow cells into...
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