Article
Telomerase activity in breast cancer patients: association with poor prognosis and more aggressive phenotype.
Medical oncology (Northwood, London, England) - 1 Mar 2016
Kulić Ana, Plavetić Natalija Dedić, Gamulin Stjepan, Jakić-Razumović Jasminka, Vrbanec Damir, Sirotković-Skerlev Maja
Abstract excerpt
Telomerase expression is an important mechanism of tumor unlimited replicative potential. The aim of this study was to evaluate prognostic impact of telomerase activity in breast cancer patients and to correlate telomerase activity with established prognostic factors. We analyzed tissue of 102 malignant breast lesions and 20 healthy breast tissues. Telomerase activity was determined by telomeric repeat...
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