MNSs genotyping by MALDI-TOF MS shows high concordance with serology, allows gene copy number testing and reveals new St(a) alleles.

doi:10.1111/bjh.14095

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Article

MNSs genotyping by MALDI-TOF MS shows high concordance with serology, allows gene copy number testing and reveals new St(a) alleles.

British journal of haematology - 1 Aug 2016

Meyer Stefan, Vollmert Caren, Trost Nadine, Sigurdardottir Sonja, Portmann Claudia, Gottschalk Jochen, Ries Judith, Markovic Alexander, Infanti Laura, Buser Andreas, Amar El Dusouqui Soraya, Rigal Emmanuel, Castelli Damiano, Weingand Bettina, Maier Andreas, Mauvais Simon M, Sarraj Amira, Braisch Monica C, Thierbach Jutta, Hustinx Hein, Frey Beat M, Gassner Christoph

Abstract excerpt

Results of genotyping with true high-throughput capability for MNSs antigens are underrepresented, probably because of technical issues, due to the high level of nucleotide sequence homology of the paralogous genes GYPA, GYPB and GYPE. Eight MNSs-specific single nucleotide polymorphisms (SNP) were detected using matrix-assisted laser desorption/ionization, time-of-flight mass spectrometry (MALDI-TOF MS) in 5800...

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PMID: 27072601
DOI: 10.1111/bjh.14095

Genes

GYPB
GYPE
GYPA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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