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Article

The YY1 / MMP2 axis promotes trophoblast invasion at the maternal–fetal interface

1 Feb 2016

Abstract excerpt

YY1 is a sequence-specific DNA-binding transcription factor that has many important biological roles. However, its function in trophoblasts at the maternal-fetal interface remains to be elucidated. In this study, we used an mRNA microarray and reverse transcription qPCR and compared the YY1 mRNA expression level in trophoblasts between patients with recurrent miscarriage (RM) and healthy control subjects. Our...

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Share to Pregnancy and preeclampsia studies
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PMID: 27071480
DOI: 10.1002/path.4694

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