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Article

Hyaluronan Modulation Impacts Staphylococcus aureus Biofilm Infection.

Infection and immunity - 1 Jun 2016

Ibberson Carolyn B, Parlet Corey P, Kwiecinski Jakub, Crosby Heidi A, Meyerholz David K, Horswill Alexander R

Abstract excerpt

Staphylococcus aureus is a leading cause of chronic biofilm infections. Hyaluronic acid (HA) is a large glycosaminoglycan abundant in mammalian tissues that has been shown to enhance biofilm formation in multiple Gram-positive pathogens. We observed that HA accumulated in an S. aureus biofilm infection using a murine implant-associated infection model and that HA levels increased in a mutant strain lacking...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27068096
DOI: 10.1128/IAI.01418-15
PMCID: PMC4907140

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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