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Article

Alpha-Toxin Contributes to Biofilm Formation among Staphylococcus aureus Wound Isolates.

Toxins - 16 Apr 2018

Anderson Michele J, Schaaf Emily, Breshears Laura M, Wallis Heidi W, Johnson James R, Tkaczyk Christine, Sellman Bret R, Sun Jisun, Peterson Marnie L

Abstract excerpt

Biofilms complicate treatment of Staphylococcus aureus (SA) wound infections. Previously, we determined alpha-toxin (AT)-promoted SA biofilm formation on mucosal tissue. Therefore, we evaluated SA wound isolates for AT production and biofilm formation on epithelium and assessed the role of AT in biofilm formation. Thirty-eight wound isolates were molecularly typed by pulsed-field gel electrophoresis (PFGE),...

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Identifiers

PMID: 29659477
DOI: 10.3390/toxins10040157
PMCID: PMC5923323

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