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Article

Antigenic features of foot-and-mouth disease virus serotype Asia1 as revealed by monoclonal antibodies and neutralization-escape mutants.

Virus research - 1 Aug 1997

Sanyal A, Venkataramanan R, Pattnaik B

Abstract excerpt

Neutralizable antigenic sites/epitopes of serotype Asial foot-and-mouth disease virus (strain IND63/72) were identified using monoclonal antibodies (mabs) and their neutralization-escape mutants. Relative affinity/reactivity of the mabs for viral (both native and trypsin-cleaved) and subviral antigens in enzyme-linked immunosorbent assay (ELISA) showed dominance of trypsin-sensitive and conformation-dependent...

Topics

Animals
Antibodies, Monoclonal
Antibodies, Viral
Antigens, Viral
Aphthovirus
Cattle
Enzyme-Linked Immunosorbent Assay
Foot-and-Mouth Disease
Mutation
Neutralization Tests
Serotyping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9282776
DOI: 10.1016/s0168-1702(97)00058-0

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