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Article

Inactivation of semicarbazide-sensitive amine oxidase induces the phenotypic switch of smooth muscle cells and aggravates the development of atherosclerotic lesions.

Atherosclerosis - 1 Jun 2016

Zhang Miao, Liu Limin, Zhi Feng, Niu Panpan, Yang Mengya, Zhu Xuemei, Diao Ying, Li Yanmei, Wang Jun, Zhao Ying

Abstract excerpt

BACKGROUND AND AIMS: Clinical studies have demonstrated that serum semicarbazide-sensitive amine oxidase (SSAO) activities positively correlate with the progression of atherosclerosis. The aim of the present study is to investigate the effect of SSAO inactivation on the development of atherosclerosis. METHODS: Female LDLr knockout (KO) mice were given the Western-type diet for 6 and 9 weeks to induce the...

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Identifiers

PMID: 27065245
DOI: 10.1016/j.atherosclerosis.2016.03.039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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