Article
Mutations in the C-terminal region affect subcellular localization of crucian carp herpesvirus (CaHV) GPCR.
Virus genes - 1 Aug 2016
Wang Jun, Gui Lang, Chen Zong-Yan, Zhang Qi-Ya
Abstract excerpt
G protein-coupled receptors (GPCRs) are known as seven transmembrane domain receptors and consequently can mediate diverse biological functions via regulation of their subcellular localization. Crucian carp herpesvirus (CaHV) was recently isolated from infected fish with acute gill hemorrhage. CaHV GPCR of 349 amino acids (aa) was identified based on amino acid identity. A series of variants with...
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