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Article

Cytoplasmic tail of coronavirus spike protein has intracellular targeting signals.

Journal of biosciences - 1 Jun 2017

Sadasivan Jibin, Singh Manmeet, Sarma Jayasri DAS

Abstract excerpt

Intracellular trafficking and localization studies of spike protein from SARS and OC43 showed that SARS spike protein is localized in the ER or ERGIC compartment and OC43 spike protein is predominantly localized in the lysosome. Differential localization can be explained by signal sequence. The sequence alignment using Clustal W shows that the signal sequence present at the cytoplasmic tail plays an important...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28569247
DOI: 10.1007/s12038-017-9676-7
PMCID: PMC7091306

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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