Article
The roles of grouper clathrin light chains in regulating the infection of a novel marine DNA virus, Singapore grouper iridovirus.
Scientific reports - 30 Oct 2019
Wang Liqun, Li Qiang, Ni Songwei, Huang Youhua, Wei Jingguang, Liu Jiaxin, Yu Yepin, Wang Shaowen, Qin Qiwei
Abstract excerpt
Clathrins, composed of clathrin heavy chains (CHCs) and clathrin light chains (CLCs), are usually hijacked by viruses for infection. However, the role of CLCs, especially in regulating fish virus infection, remains poorly understood. Here, two isoforms of CLCs were cloned from the red-spotted grouper (Epinephelus akaara) (EaCLCa and EaCLCb). Both EaCLC transcripts were expressed in all examined tissues, and the...
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