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Article

Perspectives on genetic studies of type 2 diabetes from the genome-wide association studies era to precision medicine.

Journal of diabetes investigation - 1 Apr 2024

Imamura Minako, Maeda Shiro

Abstract excerpt

Genome-wide association studies (GWAS) have facilitated a substantial and rapid increase in the number of confirmed genetic susceptibility variants for complex diseases. Approximately 700 variants predisposing individuals to the risk for type 2 diabetes have been identified through GWAS until 2023. From 2018 to 2022, hundreds of type 2 diabetes susceptibility loci with smaller effect sizes were identified through...

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Identifiers

PMID: 38259175
DOI: 10.1111/jdi.14149
PMCID: PMC10981147

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