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Signaling Networks Determining Life Span

2 Jun 2016

Abstract excerpt

The health of an organism is orchestrated by a multitude of molecular and biochemical networks responsible for ensuring homeostasis within cells and tissues. However, upon aging, a progressive failure in the maintenance of this homeostatic balance occurs in response to a variety of endogenous and environmental stresses, allowing the accumulation of damage, the physiological decline of individual tissues, and...

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PMID: 27294438
DOI: 10.1146/annurev-biochem-060815-014451

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