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Article

Electrogenic Steps Associated with Substrate Binding to the Neuronal Glutamate Transporter EAAC1.

The Journal of biological chemistry - 27 May 2016

Tanui Rose, Tao Zhen, Silverstein Nechama, Kanner Baruch, Grewer Christof

Abstract excerpt

Glutamate transporters actively take up glutamate into the cell, driven by the co-transport of sodium ions down their transmembrane concentration gradient. It was proposed that glutamate binds to its binding site and is subsequently transported across the membrane in the negatively charged form. With the glutamate binding site being located partially within the membrane domain, the possibility has to be...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27044739
DOI: 10.1074/jbc.M116.722470
PMCID: PMC4882452

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