Article
KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR GENES AND THEIR HLA-C LIGANDS IN HASHIMOTO THYROIDITIS IN A CHINESE POPULATION.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists - 1 Aug 2016
Li Jian-Ting, Guo Cheng, Li Ming-Long, Wei Yong-Qing, Hou Yan-Feng, Jiao Yu-Lian, Zhao Yue-Ran, Sun Hui, Xu Jin, Cao Ming-Feng, Feng Li, Yu Gui-Na, Gao Ling, Liu Yi-Qing, Zhang Bing-Chang, Zhao Jia-Jun, Zhang Hai-Qing
Abstract excerpt
OBJECTIVE: Natural killer (NK) cells serve as primary immune surveillance and are partially regulated by combinations of killer immunoglobulin-like receptors (KIR) and their human leukocyte antigen-C (HLA-C) ligands. Alterations in NK cell activity have been associated with Hashimoto thyroiditis (HT). The aim of this study was to determine whether certain KIR/HLA-C genotype combinations play a role in HT...
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