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Article

Association of the Genetic Diversity of Killer Cell Immunoglobulin-like Receptor Genes and HLA-C Ligand in Saudi Women With Thyroid Cancer.

Cancer control : journal of the Moffitt Cancer Center - 1 Jan 2000

Altalhi Razan A, Aljuaimlani Ali, Alswayyed Mohammed, Arafah Maha, Tashkandy Yusra, Almutairi Bader O, Mansour Lamjed, Alomar Suliman Y

Abstract excerpt

INTRODUCTION: Genetic diversity in the killer immunoglobulin-like receptor (KIR) gene composition and human leukocyte antigen (HLA) class I ligands, such as HLA-C, can affect the activity of natural killer cells and determine anti-cancer immunity. Specific KIR-HLA combinations can enhance cancer predisposition by promoting immune evasion. Studying the relationship between KIR-HLA polymorphisms and thyroid cancer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-C Antigens

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Share to Polymorphism, Genetic

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Source

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Identifiers

PMID: 39365900
DOI: 10.1177/10732748241274495
PMCID: PMC11452862

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