Article
Metabolic model of Synechococcus sp. PCC 7002: Prediction of flux distribution and network modification for enhanced biofuel production.
Bioresource technology - 1 Aug 2016
Hendry John I, Prasannan Charulata B, Joshi Aditi, Dasgupta Santanu, Wangikar Pramod P
Abstract excerpt
Flux Balance Analysis was performed with the Genome Scale Metabolic Model of a fast growing cyanobacterium Synechococcus sp. PCC 7002 to gain insights that would help in engineering the organism as a production host. Gene essentiality and synthetic lethality analysis revealed a reduced metabolic robustness under genetic perturbation compared to the heterotrophic bacteria Escherichia coli. Under glycerol...
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