Article
Metabolomic analysis reveals functional overlapping of three signal transduction proteins in regulating ethanol tolerance in cyanobacterium Synechocystis sp. PCC 6803.
Molecular bioSystems - 1 Mar 2015
Zhu Ye, Pei Guangsheng, Niu Xiangfeng, Shi Mengliang, Zhang Mingyang, Chen Lei, Zhang Weiwen
Abstract excerpt
Low ethanol tolerance is a crucial factor that restricts the feasibility of bioethanol production in renewable cyanobacterial systems. Our previous studies showed that several transcriptional regulators were differentially regulated by exogenous ethanol in Synechocystis. In this study, by constructing knockout mutants of 34 Synechocystis putative transcriptional regulator-encoding genes and analyzing their...
Topics
- Adaptation, Biological
- Bacterial Proteins
- Cluster Analysis
- Cyanobacteria
- Ethanol
- Gene Expression Regulation, Bacterial
- Gene Knockout Techniques
- Metabolic Networks and Pathways
- Metabolome
- Metabolomics
- Mutation
- Transcription, Genetic