Article
Carbon sink removal: Increased photosynthetic production of lactic acid by Synechocystis sp. PCC6803 in a glycogen storage mutant.
Journal of biotechnology - 20 Aug 2014
van der Woude Aniek D, Angermayr S Andreas, Puthan Veetil Vinod, Osnato Anna, Hellingwerf Klaas J
Abstract excerpt
Deletion of pathways for carbon-storage in the cyanobacterium Synechocystis sp. PCC6803 has been suggested as a strategy to increase the size of the available pyruvate pool for the production of (heterologous) chemical commodities. Here we show that deletion of the pathway for glycogen synthesis leads to a twofold increased lactate production rate, under nitrogen-limited conditions, whereas impairment of...
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