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Article

Progesterone receptor-dependent regulation of genes in the oviducts of female mice

11 Jun 2014

Abstract excerpt

Oviducts play a critical role in gamete and embryo transport, as well as supporting early embryo development. Progesterone receptor (PGR) is a transcription factor highly expressed in oviductal cells, while its activating ligand, progesterone, surges to peak levels as ovulation approaches. Progesterone is known to regulate oviduct cilia beating and muscular contractions in vitro, but how PGR may mediate this in...

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PMID: 24916968
DOI: 10.1152/physiolgenomics.00044.2014

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