Article
Endoplasmic Reticulum Stress Induced Synthesis of a Novel Viral Factor Mediates Efficient Replication of Genotype-1 Hepatitis E Virus.
PLoS pathogens - 1 Apr 2016
Nair Vidya P, Anang Saumya, Subramani Chandru, Madhvi Abhilasha, Bakshi Karishma, Srivastava Akriti, Shalimar, Nayak Baibaswata, Ranjith Kumar C T, Surjit Milan
Abstract excerpt
Hepatitis E virus (HEV) causes acute hepatitis in many parts of the world including Asia, Africa and Latin America. Though self-limiting in normal individuals, it results in ~30% mortality in infected pregnant women. It has also been reported to cause acute and chronic hepatitis in organ transplant patients. Of the seven viral genotypes, genotype-1 virus infects humans and is a major public health concern in...
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