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Somatic Comorbidity in Schizophrenia: Some Possible Biological Mechanisms Across the Life Span

31 Mar 2016

Abstract excerpt

Schizophrenia is associated with decreased life expectancy (15-25 y) compared to the general population, with comorbid somatic diseases and in particular cardiovascular diseases being a major cause. Life style and medication probably account for much of the increased mortality risk due to somatic diseases in schizophrenia, but the evidence implicating biological pathways potentially affecting both body and brain...

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PMID: 27033328
DOI: 10.1093/schbul/sbw028

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