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Article

Cystic fibrosis: a model system for precision medicine.

Current opinion in pediatrics - 1 Jun 2016

Martiniano Stacey L, Sagel Scott D, Zemanick Edith T

Abstract excerpt

PURPOSE OF REVIEW: Development of cystic fibrosis transmembrane conductance regulator (CFTR) modulators, small molecule therapies that target the basic defect in cystic fibrosis (CF), represents a new era in CF treatment. This review highlights recent progress in CF therapeutics as an example of precision medicine and personalized approaches to test CFTR modulators using preclinical model systems. RECENT...

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Source

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Identifiers

PMID: 27031658
DOI: 10.1097/MOP.0000000000000351
PMCID: PMC4946574

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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