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Cystic fibrosis transmembrane conductance regulator modulators: precision medicine in cystic fibrosis

13 Mar 2018

Abstract excerpt

PURPOSE OF REVIEW: The aim of this study was to describe the newest development in cystic fibrosis (CF) care, CF transmembrane conductance regulator (CFTR) modulator therapies. RECENT FINDINGS: Phase II results showing CFTR modulator triple therapies are more effective than current CFTR modulators. SUMMARY: CFTR modulator therapy targets the protein defective in CF and boosts its function, but the drug must match...

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PMID: 29538046
DOI: 10.1097/mop.0000000000000627

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