Article
[Treatment of Cystic Fibrosis with CFTR Modulators].
Pneumologie (Stuttgart, Germany) - 1 May 2016
Tümmler B
Abstract excerpt
Personalized medicine promises that medical decisions, practices and products are tailored to the individual patient. Cystic fibrosis, an inherited disorder of chloride and bicarbonate transport in exocrine glands, is the first successful example of customized drug development for mutation-specific therapy. There are two classes of CFTR modulators: potentiators that increase the activity of CFTR at the cell...
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