Article
The MKK7 p.Glu116Lys Rare Variant Serves as a Predictor for Lung Cancer Risk and Prognosis in Chinese.
PLoS genetics - 1 Mar 2016
Qiu Fuman, Yang Lei, Lu Xiaoxiao, Chen Jiansong, Wu Di, Wei Yongfang, Nong Qingqing, Zhang Lisha, Fang Wenxiang, Chen Xiaoliang, Ling Xiaoxuan, Yang Binyao, Zhang Xin, Zhou Yifeng, Lu Jiachun
Abstract excerpt
Accumulated evidence indicates that rare variants exert a vital role on predisposition and progression of human diseases, which provides neoteric insights into disease etiology. In the current study, based on three independently retrospective studies of 5,016 lung cancer patients and 5,181 controls, we analyzed the associations between five rare polymorphisms (i.e., p.Glu116Lys, p.Asn118Ser, p.Arg138Cys,...
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